Table 3 Age-standardised incidence rates (n/100 000 (95% CI)a; ASR (Europe)) of MM pre SCREEN, during the SCREEN project and post SCREEN, and absolute differences in incidence rates

From: Skin cancer screening participation and impact on melanoma incidence in Germany – an observational study on incidence trends in regions with and without population-based screening

  SH SL P for comparison of SH and SL
  Women Men Women Men Women Men
Incidence rate ASR (Europe)
 Pre-SCREEN period (January 1998–December 2000)
In situ MM (ICD-10 D03) 5.7 (5.0; 6.4) 3.7 (3.2; 4.3) 2.4 (1.8; 3.2) 1.0 (0.6; 1.6) <0.001 <0.001
Invasive MM (ICD-10 C43) 16.8 (15.7; 18.0) 15.2 (14.1; 16.4) 9.2 (7.8; 10.6) 10.7 (9.3; 12.4) <0.001 <0.001
 SCREEN period (July 2003–June 2004)
In situ MM (ICD-10 D03) 13.3 (11.5; 15.2) 7.7 (6.4; 9.2) 3.5 (2.1; 5.3) 3.1 (1.8; 4.8) <0.001 <0.001
Invasive MM (ICD-10 C43) 25.7 (23.2; 28.3) 19.2 (17.2; 21.5) 10.9 (8.4; 13.8) 11.8 (9.2; 14.9) <0.001 0.003
 Post SCREEN and pre SCEDP period (January 2005–December 2007)
In situ MM (ICD-10 D03) 10.4 (9.5; 11.4) 6.6 (5.9; 7.3) 4.0 (3.1; 5.0) 3.6 (2.8; 4.6) <0.001 <0.001
Invasive MM (ICD-10 C43) 15.1 (14.0; 16.2) 15.1 (14.1; 16.3) 12.2 (10.6; 13.9) 11.5 (10.0; 13.1) 0.044 0.002
Absolute differences in incidence rates ASR (Europe) (observed – preceding incidence as indicated above)
 SCREEN period
In situ MM (ICD-10 D03) 7.6 (5.6; 9.6) 4.0 (2.5; 5.5) 1.1 (−0.5; 2.7) 2.1 (0.6; 3.6) <0.001 0.164
Invasive MM (ICD-10 C43) 8.9 (6.1; 11.7) 4.0 (1.6; 6.4) 1.7 (−1.3; 4.7) 1.1 (−2.0; 4.2) 0.005 0.373
 Post SCREEN/pre SCS period
In situ MM (ICD-10 D03) −2.9 (−5.0; −0.8) −1.1 (−2.7; 0.5) 0.5 (−1.2; 2.2) 0.5 (−1.2; 2.2) 0.019 0.264
Invasive MM (ICD-10 C43) −10.6 (−13.3; −7.9) −4.1 (−6.5; −1.7) 1.3 (−1.8; 4.4) −0.3 (−3.4; 2.8) <0.001 0.252
  1. Abbreviations: ASR=age-standardised incidence rates; CI=confidence intervals; MM=melanoma; SCS=skin cancer screening; SCEDP=Skin Cancer Early Detection Program; SCREEN=Skin Cancer Research to provide Evidence for Effectiveness of Screening in Northern Germany; SH=Schleswig-Holstein; SL=Saarland.
  2. aPoisson-based 95% CI.