Table 1 Clinical and histological characteristics of the patients whose samples were used for simulated prostate biopsies

From: Highly sensitive molecular diagnosis of prostate cancer using surplus material washed off from biopsy needles

Tumoural samples   Normal samples a  
Number of samples 37 Number of samples 11
Number of patients 27 Number of patients 6
Mean age (years) 62.32 (49–72) Mean age (years) 68.5 (57–82)
Mean PSA (ng ml−1) 10.13 (3.09–55.8) Mean PSA (ng ml−1)b 4.93 (2–7.1)
Median PSA (ng ml−1) 8 Median PSA (ng ml−1)b 5.3
Mean ratio free PSA/total PSA (%)c 15.3 (3.4–51.4) Mean ratio free PSA/total PSA (%)b 23.47 (18.1–33.2)
Median ratio free PSA/total PSA (%)c 10 Median ratio free PSA/total PSA (%)b 21.3
Gleason score (number of patients)
 5 3   
 6 3   
 7 17   
 8 2   
 9 2   
TNM stage (number of patients)
 T2 15   
 T3 12   
% of carcinoma in the tissue cored 38.4(<10–90)   
  1. Abbreviation: PSA=prostate-specific antigen.
  2. aNormal samples were obtained from tumour-free prostates from nodular hyperplasias and radical cystoprostatectomies.
  3. bData not available for two patients.
  4. cData not available for 10 patients.
  5. dMean content of tumoural glands relative to the whole tissue.