Table 1 Correlation between the phosphorylation of Akt on Thr308 or Ser473 and the phosphorylation of downstream Akt substrates

From: Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer

  pPRAS40 pTSC2 pTBC1D4
Akt-pThr308
R 0.752 0.676 0.465
p <0.1 × 10–3 <0.1 × 10–3 8.3 × 10–3
Akt-pSer473
R 0.352 0.229 0.137
p 0.052 0.216 0.462
  1. Abbreviations: Ser473=serine 473; Thr308=threonine 308.
  2. The table provides the correlation coefficient (R) and degree of significance (p) obtained for each variable shown using the Spearman's pair-wise correlation test.