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  • Experimental Oncology
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Fatty acid control of growth of human cervical and endometrial cancer cells

British Journal of Cancer volume 61, pages 500–503 (1990)Cite this article

Abstract

Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor number or affinity.

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Authors and Affiliations

  1. Institute of Obstetrics and Gynaecology, Hammersmith Hospital, London, UK

    RP Gleeson

Authors
  1. RP Gleeson
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  2. M Ayub
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  3. JT Wright
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  4. CB Wood
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  5. NA Habib
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  6. WP Soutter
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  7. MHF Sullivan
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  8. JO White
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Gleeson, R., Ayub, M., Wright, J. et al. Fatty acid control of growth of human cervical and endometrial cancer cells. Br J Cancer 61, 500–503 (1990). https://doi.org/10.1038/bjc.1990.113

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  • DOI: https://doi.org/10.1038/bjc.1990.113

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