Abstract
Human gastric carcinomas were tested for their immunohistochemical reactivity with anti-type I procollagen antiserum. In all specimens of scirrhous carcinomas, staining of the tumour cells was strongly positive, while in medullary carcinomas staining of the tumour cells was generally poor. These results suggest that the tumour cells in scirrhous carcinomas produce collagen in their stroma.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 24 print issues and online access
$259.00 per year
only $10.79 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Niitsu, Y., Ito, N., Kohda, K. et al. Immunohistochemical identification of type I procollagen in tumour cells of scirrhous adenocarcinoma of the stomach. Br J Cancer 57, 79–82 (1988). https://doi.org/10.1038/bjc.1988.13
Issue Date:
DOI: https://doi.org/10.1038/bjc.1988.13
This article is cited by
-
Overexpression of TGF-β by infiltrated granulocytes correlates with the expression of collagen mRNA in pancreatic cancer
British Journal of Cancer (2004)
-
Breast tumour cell-induced down-regulation of type I collagen mRNA in fibroblasts
British Journal of Cancer (1999)
