Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Immunoadherence and complement in cancer-bearing mice

British Journal of Cancer volume 37, pages 23–27 (1978)Cite this article

Abstract

Shortly after grafting of Ehrlich ascites carcinoma cells, the serum of tumour-bearing mice loses the capacity to mediate immunoadherence phenomena, because of a sharp decrease in the concentration of C3b and C3d, while the cellular receptors for such factors are unaffected by tumour growth. It is suggested that complement is consumed through the alternative pathway which is activated during the inflammatory responses accompanying tumour growth.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Get just this article for as long as you need it

$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Authors
  1. C Porta
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M L Villa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E Clerici
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Porta, C., Villa, M. & Clerici, E. Immunoadherence and complement in cancer-bearing mice. Br J Cancer 37, 23–27 (1978). https://doi.org/10.1038/bjc.1978.3

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/bjc.1978.3

Search

Advanced search

Quick links