Abstract
Mice were given a single dose of nitrosolimethylamine, nitrosoliethylamine or nitrosomethylethylamine and the yield of tumours and related lesions in the livers determined 12 months later. A hepatonecrotic dose of CCl4 24 or 48 h before the nitrosamines, increased the yields of hepatocellular tumours and proliferative foci in the livers, whereas when given 60 h before the nitrosamines there was no significant effect.
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Pound, A. Influence of carbon tetrachloride on induction of tumours of the liver and kidneys in mice by netrosamines. Br J Cancer 37, 67–75 (1978). https://doi.org/10.1038/bjc.1978.10
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DOI: https://doi.org/10.1038/bjc.1978.10