Abstract
In mice, i.v. C. parvum induces intravascular coagulation. This is a prolonged reaction lasting up to 7 days. It results in thrombosis in hepatic vessels with consequent hepatic necrosis, and thrombosis in pulmonary and splenic vessels. This may be important in the assessment of the tumour-inhibitory activity of C. parvum.
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Lampert, I., Jones, P., Sadler, T. et al. Intravascular coagulation resulting from intravenous injection of C. parvum in mice. Br J Cancer 36, 15–22 (1977). https://doi.org/10.1038/bjc.1977.149
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DOI: https://doi.org/10.1038/bjc.1977.149