Abstract
In two separate experiments benzopyrene has been painted regularly on the backs of mice at difference dose levels.
It has been shown that the incidence rate of both tumours and infiltrating carcinomas can be taken as proportional to d2(t — w)k where t is time from first application, w and k are constants independent of dose, and d is the applied dose.
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Lee, P., O'Neill, J. The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments. Br J Cancer 25, 759–770 (1971). https://doi.org/10.1038/bjc.1971.90
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DOI: https://doi.org/10.1038/bjc.1971.90
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