Table 2 Mixed effect model analysis of 24-week repaglinide treatment effect, genotypes effect and their interaction effect.

From: A variation in NOS1AP gene is associated with repaglinide efficacy on insulin resistance in type 2 diabetes of Chinese

Parameters Repaglinide treatment effect (P value) Genotypes effect (P value) Genotypes and treatment interaction effect (P value)
BMI(kg/m2) 0.039 0.064 0.198
Waist-hip ratio 0.907 0.804 0.527
Glycated hemoglobin (%) <0.001 0.427 0.585
Fasting plasma glucose (mmol/L) <0.001 0.631 0.573
2-h Plasma glucose (mmol/L) <0.001 0.494 0.328
HOMA-IR 0.056 0.824 0.013
HOMA-B <0.001 0.881 0.806
Fasting insulin (pmol/L) <0.001 0.812 0.103
Acute insulin secretion(pmol/L) 0.270 0.875 0.395
Acute insulin secretion (pmol/L)/Plasma glucose (mmol/L) 0.769 0.032 0.738