Figure 5 | Cancer Gene Therapy

Figure 5

From: Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small-cell lung cancer cells

Figure 5

Effect of Ad5 on PTX-induced apoptosis. The fraction of sub-G1 cells was measured by FACS analysis of propidium iodide (PI)-stained cells at 6 and 24 h post-infection at an MOI of 100 with(out) 10 or 50 nM PTX. Values are the mean (n=3)±s.d. The P-values were calculated by comparing the fraction of apoptotic cells after infection with Ad5 alone or in combination with different concentrations of PTX at a certain time point using Student's t-test.

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