Figure 2 | Cancer Gene Therapy

Figure 2

From: Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small-cell lung cancer cells

Figure 2

PTX enhances adenoviral gene expression in a concentration-dependent manner. The levels of expression of adenoviral E1A13S, Pol, ADP and Pent were measured within 48 h after Ad5 infection at an MOI of 100, solely or in combination with different concentration of PTX. Values are the mean (n=3)±s.d. The P-values were calculated by comparing the expression of each gene in cells infected with Ad5 alone or in combination with different concentrations of PTX at a given time point using Student's t-test.

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