Figure 5 | Cancer Gene Therapy

Figure 5

From: In vitro activation of cancer patient–derived dendritic cells by tumor cells genetically modified to express CD154

Figure 5

Activation of autologous DCs from patients with RCC. RCC cells from three patients were transduced with Ad-CD154 or Ad-dl70-3. RCC cells expressing CD154 up-regulated expression of CD83 and CD86 molecules on cocultured autologous DCs from the same patient. White histograms represent cell surface marker expression whereas filled histograms represent staining with irrelevant isotype matched control mAbs.

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