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Effects of breast feeding on neuropsychological development in a community with methylmercury exposure from seafood

Journal of Exposure Science & Environmental Epidemiology volume 15, pages 423–430 (2005)Cite this article

Abstract

Breastfeeding has been associated with an advantage to infant neurobehavioral development, possibly in part due to essential nutrients in breast milk. However, breast milk may be contaminated by environmental neurotoxicants, such as methylmercury. In the Faroe Islands, where maternal consumption of pilot whale may cause transfer of marine toxicants into breast milk, a cohort of 1022 consecutive singleton births was generated during 1986–87. Methylmercury exposure was assessed from mercury concentrations in cord blood and in the hair of the child at age 12 months, and the duration of breastfeeding was recorded. At approximately 7 years of age, 917 (90%) of the children underwent detailed neurobehavioral examination. After adjustment for confounders, breastfeeding was associated with only marginally better neuropsychological performance on most tests. These associations were robust even after adjustment for cord-blood and hair mercury concentration at age 1 year. Thus, in this cohort of children with a relatively high prenatal toxicant exposure and potential exposure to neurotoxicants through breast milk, breastfeeding was associated with less benefits on neurobehavioral development than previously published studies though not associated with a deficit in neuropsychological performance at age 7. Although the advantage may be less, Faroese women can still safely breastfeed their children.

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Acknowledgements

This work was supported by grants from the US National Institute of Environmental Health Sciences (ES06112), the European Commission (Environmental Research Programme), the Danish Medical Research Council (Grant No. SV1736), and the Dannin Foundation.

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Authors and Affiliations

  1. Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Winsloewsparken 17, Odense C, Denmark

    Tina Kold Jensen, Philippe Grandjean, Esben Budtz Jørgensen, Frodi Debes & Pál Weihe

  2. Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA

    Philippe Grandjean

  3. Department of Biostatistics, Panum Institute, University of Copenhagen, Copenhagen, Denmark

    Esben Budtz Jørgensen

  4. Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, USA

    Roberta F White

  5. Department of Occupational and Public Health, The Faroese Hospital System, Tórshavn, Faroe Islands

    Frodi Debes & Pál Weihe

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  1. Tina Kold Jensen
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  2. Philippe Grandjean
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  3. Esben Budtz Jørgensen
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  4. Roberta F White
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  5. Frodi Debes
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  6. Pál Weihe
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Correspondence to Tina Kold Jensen.

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Jensen, T., Grandjean, P., Jørgensen, E. et al. Effects of breast feeding on neuropsychological development in a community with methylmercury exposure from seafood. J Expo Sci Environ Epidemiol 15, 423–430 (2005). https://doi.org/10.1038/sj.jea.7500420

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  • DOI: https://doi.org/10.1038/sj.jea.7500420

Keywords

  • breast feeding
  • environmental pollution
  • neuropsychological tests
  • pre school child
  • food contamination
  • methylmercury compounds

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