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Toying with memory in the hippocampus

Mice lacking NMDA receptors in hippocampal area CA1 are deficient in spatial memory. They also have nonspatial memory deficits, which are overcome by environmental enrichment.

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Figure 1: Environmental enrichment increases the connections within the hippocampus and neocortex.

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Eichenbaum, H., Harris, K. Toying with memory in the hippocampus. Nat Neurosci 3, 205–206 (2000). https://doi.org/10.1038/72901

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