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  • Letter to the Editor
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Nasopharyngeal Surfactant Administration to Prevent Neonatal Respiratory Distress Syndrome

Journal of Perinatology volume 25, pages 361–362 (2005)Cite this article

Dear Editor:

We read with interest Kattwinkel et al.'s1 article “Technique for Intrapartum Administration of Surfactant without Requirement for an Endotracheal Tube”, and applaud the authors for their efforts in this feasibility study investigating early, easy techniques to reduce the incidence of neonatal respiratory distress syndrome (RDS). In the event, the authors or others wish to pursue investigation of the utility of this technique, we wish to raise certain issues that need to be addressed as part of investigating the feasibility of applying this technique in clinical practice.

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References

  1. Kattwinkel J, Robinson M, Bloom BT, Delmore P, Ferguson JE . Technique for intrapartum administration of surfactant without requirement for an endotracheal tube. J Perinatol 2004;24(6):360–365.

    Article  CAS  Google Scholar 

  2. Enhorning G, Grossmann G, Robertson B . Pharyngeal deposition of surfactant in the premature rabbit fetus. Biol Neonate 1973;22(1):126–132.

    Article  CAS  Google Scholar 

  3. Enhorning G, Robertson B, Milne E, Wagner R . Radiologic evaluation of the premature newborn rabbit after pharyngeal deposition of surfactant. Am J Obstet Gynecol 1975;121(4):475–480.

    Article  CAS  Google Scholar 

  4. Hirschl RB . Current experience with liquid ventilation. Paediatr Respir Rev 2004;5(Suppl A):S339–S345.

    Article  Google Scholar 

  5. Leach CL, Greenspan JS, Rubenstein SD, et al. Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. The LiquiVent Study Group. N Engl J Med 1996;335(11):761–767.

    Article  CAS  Google Scholar 

  6. von der Hardt K, Schoof E, Kandler MA, Dotsch J, Rascher W . Aerosolized perfluorocarbon suppresses early pulmonary inflammatory response in a surfactant-depleted piglet model. Pediatr Res 2002;51(2):177–182.

    Article  CAS  Google Scholar 

  7. von der Hardt K, Kandler MA, Brenn G, et al. Comparison of aerosol therapy with different perfluorocarbons in surfactant-depleted animals. Crit Care Med 2004;32(5):1200–1206.

    Article  CAS  Google Scholar 

  8. Horbar JD, Carpenter JH, Buzas J, et al., for the members of the Vermont Oxford Network. Timing of initial surfactant treatment for infants 23 to 29 weeks’ gestation: is routine practice evidence based? Pediatrics 2004;113(6):1593–1602.

    Article  Google Scholar 

  9. Soll RF, Morley CJ . Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants. Cochrane Database Syst Rev 2001; (2):CD000510.

  10. Dunn MS, Reilly MC . Approaches to the initial respiratory management of preterm neonates. Paediatr Respir Rev 2003;4(1):2–8.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA

    Caraciolo J Fernandes MD & David A Horst MD

  2. Department of Pediatrics, University College Hospital, Galway, Ireland

    Donough J O'Donovan MD

Authors
  1. Caraciolo J Fernandes MD
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  2. David A Horst MD
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  3. Donough J O'Donovan MD
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Fernandes, C., Horst, D. & O'Donovan, D. Nasopharyngeal Surfactant Administration to Prevent Neonatal Respiratory Distress Syndrome. J Perinatol 25, 361–362 (2005). https://doi.org/10.1038/sj.jp.7211264

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  • DOI: https://doi.org/10.1038/sj.jp.7211264

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