Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Perinatal/Neonatal Case Presentation
  • Published:

Perinatal/Neonatal Case Presentation

Sirenomelia with an Angiomatous Lumbosacral Myelocystocele in a Full-term Infant


Sirenomelia, also known as the mermaid syndrome, is a rare congenital malformation of uncertain etiology. It is characterized by fusion of the lower limbs and commonly associated with severe urogenital and gastrointestinal malformations. In this report, we describe the first case of an infant with sirenomelia and a massive angiomatous lumbosacral myelocystocele.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1
Figure 2
Figure 3

Similar content being viewed by others


  1. Stocker JT, Heifetz SA, Sirenomelia . A morphological study of 33 cases and review of the literature. Perspect Pediatr Pathol 1987;10:7–50.

    CAS  PubMed  Google Scholar 

  2. Duhamel B . From the mermaid to anal imperforation: the syndrome of caudal regression. Arch Dis Child 1961;36:153–5.

    Article  Google Scholar 

  3. Stevenson RE, Lyons Jones K, Phelan MC, et al. Vascular steal: the pathogenetic mechanism producing sirenomelia and associated defects of the viscera and soft tissues. Pediatre 1986;78(3):451–7.

    CAS  Google Scholar 

  4. Kallen B, Castilla EE, Lancaster PA, et al. The cyclops and the mermaid: an epidemiological study of two types of rare malformation. J Med Genet 1992;29:30–5.

    Article  CAS  Google Scholar 

  5. Schiesser M, Holzgreve W, Lapaire O, et al. Sirenomelia, the mermaid syndrome — detection in the first trimester. Prenat Diagn 2003;23:493–5.

    Article  Google Scholar 

  6. Stanton MP, Penington EC, Hutson JM . A surviving infant with sirenomelia (mermaid syndrome) associated with absent bladder. J Pediatr Surg 2003;38(8):1266–8.

    Article  Google Scholar 

  7. Murphy JJ, Fraser GC, Blair GK . Sirenomelia: case of the surviving mermaid. J Pediatr Surg 1992;27(10):1265–68.

    Article  CAS  Google Scholar 

  8. Goodlow OG, McCoy Sibley RI, Allen BG, et al. Sirenomelia: mermaid syndrome. J Natl Med Assoc 1988;80(3):343–46.

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Mclone DG, Naidich TP . Terminal myelocystocele. Neurosurgery 1985;16(1):36–43.

    CAS  PubMed  Google Scholar 

  10. Zaw W, Stone DG . Caudal regression syndrome in twin pregnancy with type II diabetes. J Perinatol 2002;22:171–4.

    Article  Google Scholar 

  11. Valenzano M, Paoletti R, Rossi A, et al. Sirenomelia. Pathological features, antenatal ultrasonographic clues, and review of current embryogenic theories. Hum Reprod Update 1999;5(1) :82–6.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

Browne, M., Fitchev, P., Adley, B. et al. Sirenomelia with an Angiomatous Lumbosacral Myelocystocele in a Full-term Infant. J Perinatol 24, 329–331 (2004).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links