Table 2 Concordances between the three CTC detection techniques

From: Circulating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT–PCR in patients with metastatic breast cancer

  K coefficient P -value Degree of agreement Agreement (%)
Comparison with the CellSearch CTC test
 AdnaTest 0.543 <0.001 Moderate 81
 RT–PCR for CK-19 0.356 0.002 Fair 72
 RT–PCR for mammaglobin 0.220 0.04 Fair 60
 RT–PCR for CK-19 and/or mammaglobin 0.203 0.04 Fair 57
Comparison with the AdnaTest
 RT–PCR for CK-19 0.415 <0.001 Moderate 78
 RT–PCR for mammaglobin 0.082 0.37 Slight 53
 RT–PCR for CK-19 and/or mammaglobin 0.109 0.189 Slight 50
  1. Abbreviations: CTC=circulating tumour cell; ER=oestrogen receptor; PR=progesterone receptor; RT–PCR=reverse transcription–PCR.