Figure 2 | British Journal of Cancer

Figure 2

From: Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

Figure 2

Electron microscopy of microvesicles isolated from urine of healthy donor (A and B) and PCa patient (patient nr. 11, C and D). (A) Microvesicles from healthy donor displaying the typical size (150–500 nm) and ultrastructure of electron-dense and electron-lucent prostasomes (arrows). (B) At high magnification, note the limiting membrane (arrowheads) and the unstructured matrix (star) of prostasomes. (C) Urine microvesicles from PCa patient showing small size (30–100 nm) and cup-shaped morphology (arrowheads) characteristic of exosomes. (D) Immunoelectron micrograph showing the presence of the typical surface exosomal marker CD63 on the microvesicles (arrowheads). Bars: A, B 500 nm; C, D 100 nm.

Back to article page