Table 3 Tumour marker accuracy and sensitivity at 95% specificity for ovarian cancer and ovarian endometriosis

From: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts

Markers Accuracy (%) ROC-AUC (%) Sensitivity (%)
OvCa vs OvEndo
 CA125+HE4 94.0 91.3 78.6
 CA125 92.8 77.0 64.3
 HE4 91.6 91.9 71.4
OvCa vs ctrl
 CA125+HE4 96.3 91.1 92.9
 CA125 96.3 91.7 78.6
 HE4 93.8 95.5 78.6
OvEndo vs ctrl
 CA125+HE4 82.2 86.8 62.3
 CA125 83.0 87.7 60.9
 HE4 60.7 60.5 5.8
OvCa vs OvEndo vs ctrl
 CA125+HE4 81.9   
 CA125 81.2   
 HE4 59.7   
  1. OvCa=ovarian cancer; OvEndo=ovarian endometriosis.