Table 3 IRR for colorectal and colon cancer according to laxative use and susceptibility to diarrhoea

From: Bowel movement frequency and risk of colorectal cancer in a large cohort study of Japanese men and women

   Colorectal cancer Colon cancer
  Observed person-years No. of cases Multivariate-adjusteda IRR 95% CIb No. of cases Multivariate-adjusteda IRR 95% CIb
Men
 Laxative use        
No 155 068 292 1.00   170 1.00  
Yes 10 015 33 1.28 0.89–1.86 20 1.31 0.81–2.11
 Susceptibility to diarrhoea        
Normal 143 808 285 1.00   168 1.00  
Having frequent diarrhoea 35 775 68 1.08 0.82–1.41 40 1.08 0.76–1.53
Women
 Laxative use        
No 206 189 183 1.00   137 1.00  
Yes 33 097 41 1.20 0.85–1.69 33 1.26 0.86–1.85
 Susceptibility to diarrhoea        
Normal 230 880 224 1.00   173 1.00  
Having frequent diarrhoea 23 417 26 1.18 0.79–1.78 16 0.95 0.57–1.59
  1. IRR=incidence rate ratios; BMI=body mass index.
  2. aAdjusted for age, BMI, intake frequency of green leafy vegetables, daily alcohol drinking, current smoking status, time spent for walking per day, family history of colorectal cancer and education.
  3. bCI: confidence interval.