Table 2 Statistical values for significant linkages obtained from whole-genome scan of an [A/J × B6] F2 population infected with C. albicans, using kidney and brain fungal loads as phenotypic traits (n=128)

From: Genetic control of suceptibility to Candida albicans in susceptible A/J and resistant C57BL/6J mice

Marker Position (cM) a Kidney fungal load Brain fungal load
   LOD χ 2 Variance explained (%) b LOD χ 2 Variance explained (%)
D2Mit81 13.5 13.5 62.1 39 12.1 55.8 36
D2Mit295 17.0 17.2 79.4 51 15.9 73.2 45
C5c 23.5 22.7c 104.6 60 19.0c 87.3 50
D2Mit458 31.7 15.4 70.8 45 12.4 57.2 38
D2Mit380 40.4 3.4 15.4 12 4.6 21.4 15
D2Mit37 45.0 2.4 10.8 8 4.1 18.7 14
  1. aThe chromosomal position of each marker is expressed as the distance from the telomere (in cM), as determined by the Mouse Genome Database Project (http://www.informatics.jax.org).
  2. bThe proportion of total phenotypic variance explained by each marker is indicated as a percentage.
  3. cHighest LOD score determined for this scan.