Kidney and brain fungal load in [A/J × B6] F2 mice infected with C. albicans. 128 [A/J × B6] F2 mice were infected i.v. with a low dose of C. albicans. Fungal load in the (a) kidney and (b) brain was measured 48 h after infection. F2 mice were separated by gender, with males displaying an overall enhanced susceptibility to infection as measured by kidney (P<0.01) but not brain CFU. Each data point represents an individual mouse, and horizontal bars represent the mean CFU counts for each group. CFU values for parental A/J and B6 mice are shown for comparison.