Table 2 Fst values for each SNP in the eight geographical regions

From: Haplotype tagging efficiency in worldwide populations in CTLA4 gene

   Sub-Saharan Africa North-Africa Middle East Europe Central/South Asia East Asia Oceania America Global a Global b
No. of populations rs i.d. 7 3 3 10 8 6 2 5 44  
−1765 T/C rs11571315 0.007 (0.61) −0.006 (0.30) 0.109 (0.24) 0.013 (0.34) 0.008 (0.30) 0.007 (0.63) 0.025 (0.26) 0.021 (0.54) 0.105 0.102
−1722 T/C rs733618 0.025 (0.90) −0.010 (0.94) 0.005 (0.87) 0.017 (0.96) 0.001 (0.88) 0.037 (0.64) −0.008 (0.99) 0.103 (0.86) 0.108 0.095
−1661 A/G rs4553808 0.036 (0.85) 0.003 (0.78) −0.001 (0.83) 0.003 (0.84) −0.016 (0.90) 0.088 (0.90) −0.027 (0.84) 0.010 (0.98) 0.034 0.015
−1577 G/A rs11571316 0.022 (0.90) 0.011 (0.57) 0.063 (0.46) 0.004 (0.49) 0.003 (0.40) 0.021 (0.71) 0.079 (0.45) 0.038 (0.54) 0.121 0.122
−658 C/T rs11571317 0.000 (1.00) 0.033 (0.94) 0.051 (0.94) 0.018 (0.90) −0.002 (0.98) 0.000 (1.00) 0.013 (0.98) 0.003 (1.00) 0.062 0.048
−319 C/T rs5742909 −0.012 (1.00) 0.012 (0.97) 0.011 (0.92) −0.014 (0.91) −0.007 (0.95) 0.039 (0.92) 0.012 (0.99) −0.002 (0.98) 0.028 0.022
+49 A/G rs231775 0.081 (0.61) −0.005 (0.72) 0.085 (0.77) 0.020 (0.72) 0.015 (0.70) 0.004 (0.36) 0.028 (0.71) 0.019 (0.50) 0.102 0.088
+6230 G/A rs3087243 0.033 (0.90) 0.004 (0.57) 0.031 (0.42) 0.003 (0.46) 0.010 (0.37) 0.028 (0.71) 0.034 (0.45) 0.031 (0.58) 0.134 0.137
+6249 G/A rs11571319 0.067 (0.76) −0.003 (0.78) −0.001 (0.88) −0.005 (0.86) −0.012 (0.91) 0.045 (0.92) −0.027 (0.85) 0.010 (0.93) 0.034 0.019
+7092 A/G rs231723 0.065 (0.66) 0.038 (0.71) 0.130 (0.55) 0.021 (0.73) 0.024 (0.68) 0.005 (0.36) 0.019 (0.64) 0.023 (0.48) 0.101 0.065
+7482 A/C rs10197010 0.099 (0.76) 0.008 (0.72) 0.012 (0.79) −0.004 (0.86) −0.013 (0.87) 0.042 (0.90) −0.027 (0.85) 0.026 (0.98) 0.037 0.017
+7982 G/A rs231725 0.114 (0.64) 0.005 (0.74) 0.083 (0.88) 0.018 (0.76) 0.039 (0.77) 0.021 (0.46) 0.004 (0.75) 0.018 (0.52) 0.125 0.105
+8173 C/T rs231726 0.160 (0.73) 0.001 (0.80) 0.076 (0.88) 0.024 (0.77) 0.032 (0.77) 0.017 (0.44) −0.009 (0.74) 0.014 (0.52) 0.122 0.097
+10 242 T/G rs11571302 0.049 (0.35) 0.001 (0.47) 0.004 (0.59) −0.002 (0.60) 0.009 (0.63) 0.049 (0.32) 0.008 (0.60) 0.031 (0.42) 0.102 0.098
+10 717 G/A rs7565213 0.041 (0.80) 0.005 (0.55) 0.010 (0.46) 0.004 (0.40) 0.007 (0.37) 0.058 (0.70) 0.008 (0.40) 0.031 (0.58) 0.104 0.098
+12 131 C/G rs10932025 0.079 (0.76) −0.005 (0.78) 0.025 (0.77) −0.006 (0.83) −0.014 (0.87) 0.042 (0.90) −0.027 (0.85) 0.044 (0.98) 0.033 0.019
+12 310 T/C rs11571297 0.052 (0.78) 0.004 (0.53) 0.004 (0.40) 0.003 (0.39) 0.010 (0.35) 0.049 (0.67) 0.008 (0.40) 0.031 (0.58) 0.101 0.095
Averagec   0.068 0.005 0.046 0.008 0.009 0.031 0.013 0.028 0.096e 0.085f
AMOVA P-valuesd   <0.001 NS <0.001 NS NS <0.001 NS 0.047 <0.001  
  1. In parentheses, median frequency of the ancestral allele (marked in bold in the first column).
  2. aGlobal comparison of all populations for each SNP.
  3. bGlobal comparison of the eight geographical groups for each SNP.
  4. cAverage Fst over all loci for each continental region.
  5. dAnalysis of the molecular variance (AMOVA). NS=not significant.
  6. eGlobal comparison of all populations for the average Fst over all loci.
  7. fGlobal comparison of the eight geographical groups for the average Fst over all loci.