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New variations in human OX40 ligand (CD134L) gene

Genes & Immunity volume 1, pages 521–522 (2000)Cite this article

Abstract

We found three new variations in the OX40 ligand (OX40L, CD134L) gene and its 5′ upstream region. −921 (G → A) at 5′ upstream region, −19 (C → G) at 5′ untranslated region, and 202+25 (G → T) at intron 2 were identified. −921 (G → A) and 202+25 (G → T) were detected in a substantial proportion of healthy Japanese individuals and were considered to be single nucleotide polymorphisms (SNPs). −19 (C → G) was detected in only one healthy individual. There was no association between these variations and the presence of rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).

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Authors and Affiliations

  1. Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, 113–0033, Japan

    K Hikami, N Tsuchiya & K Tokunaga

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  1. K Hikami
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  2. N Tsuchiya
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  3. K Tokunaga
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Corresponding author

Correspondence to N Tsuchiya.

Additional information

Sequence accession numbers: The nucleotide sequence data reported in this paper have been submitted to the DDBJ/EMBL/GenBank nucleotide sequence databases and assigned the accession numbers AB042986–AB042988. This study was supported by the Grant-in-Aid for Scientific Research (B) and Grant-in-Aid for Scientific Research on Priority Areas (C).

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Hikami, K., Tsuchiya, N. & Tokunaga, K. New variations in human OX40 ligand (CD134L) gene. Genes Immun 1, 521–522 (2000). https://doi.org/10.1038/sj.gene.6363709

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  • DOI: https://doi.org/10.1038/sj.gene.6363709

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