Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

The future of DNA sequencing

Eric D. Green, Edward M. Rubin and Maynard V. Olson speculate on the next forty years of the applications, from policing to data storage.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout


  1. Maxam, A. M. & Gilbert, W. Proc. Natl Acad. Sci. USA 74, 560–564 (1977).

    Article  ADS  CAS  Google Scholar 

  2. Sanger, F., Nicklen, S. & Coulson, A. R. Proc. Natl Acad. Sci. USA 74, 5463–5467 (1977).

    Article  ADS  CAS  Google Scholar 

  3. Shendure, J. et al. Nature (2017).

  4. Paxton, A. CAP Today (March 2017); available at

    Google Scholar 

  5. Bick, D. et al. J. Pediatr. Genet. 6, 61–76 (2017).

    CAS  PubMed  Google Scholar 

  6. Eldomery, M. K. et al. Genome Med. 9, 26 (2017).

    Article  Google Scholar 

  7. Worthey, E. A. et al. Genet. Med. 13, 255–262 (2011).

    Article  Google Scholar 

  8. Bainbridge, M. N. et al. Sci. Transl. Med. 3, 87re3 (2011).

    Article  Google Scholar 

  9. Alix-Panabières, C. & Pantel, K. Cancer Discov. 6, 479–491 (2016).

    Article  Google Scholar 

  10. Garber, K. Science 356, 1111–1112 (2017).

    Article  CAS  Google Scholar 

  11. Erlich, Y. Genome Res. 25, 1411–1416 (2015).

    Article  CAS  Google Scholar 

  12. National Research Council. Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease (National Academies Press, 2011); available at

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Eric D. Green.

Additional information

Tweet Follow @NatureNews

Related links

Related links

Related links in Nature Research

Immunology, one cell at a time 2017-Jul-03

China expands DNA data grab in troubled western region 2017-May-24

How DNA could store all the world’s data 2016-Aug-31

Pregnancy: Prepare for unexpected prenatal test results 2015-Jun-03

Related external links

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Green, E., Rubin, E. & Olson, M. The future of DNA sequencing. Nature 550, 179–181 (2017).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research