Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Neurobiology

Diversity reaches the stars

Cells called astrocytes promote and maintain neuronal function. The discovery that astrocytes vary in their gene expression, protein levels, cellular structure and function suggests that they are specialized to support distinct circuits.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Capturing variability between astrocytes.

Notes

  1. See all news & views

References

  1. Khakh, B. S. & Sofroniew, M. V. Nature Neurosci. 18, 942–952 (2015).

    Article  CAS  Google Scholar 

  2. Chai, H. et al. Neuron 95, 531–549 (2017).

    Article  CAS  Google Scholar 

  3. Ben Haim, L. & Rowitch, D. H. Nature Rev. Neurosci. 18, 31–41 (2017).

    Article  Google Scholar 

  4. Zhang, Y. & Barres, B. A. Curr. Opin. Neurobiol. 20, 588–594 (2010).

    Article  CAS  Google Scholar 

  5. Molofsky, A. V. et al. Nature 509, 189–194 (2014).

    Article  CAS  ADS  Google Scholar 

  6. Cahoy, J. D. et al. J. Neurosci. 28, 264–278 (2008).

    Article  CAS  Google Scholar 

  7. Bazargani, N. & Attwell, D. Nature Neurosci. 19, 182–189 (2016).

    Article  CAS  Google Scholar 

  8. Sloan, S. A. & Barres, B. A. Neuron 84, 1112–1115 (2014).

    Article  CAS  Google Scholar 

  9. Sanz, E. et al. Proc. Natl Acad. Sci. USA 106, 13939–13944 (2009).

    Article  CAS  ADS  Google Scholar 

  10. Srinivasan, R. et al. Neuron 92, 1181–1195 (2016).

    Article  CAS  Google Scholar 

  11. Francelle, L. et al. Hum. Mol. Genet. 24, 1563–1573 (2015).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Laura E. Clarke or Shane A. Liddelow.

Related links

Related links

Related links in Nature Research

Regeneration: Not everything is scary about a glial scar

Neuroscience: Astrocytes as aide-mémoires

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Clarke, L., Liddelow, S. Diversity reaches the stars. Nature 548, 396–397 (2017). https://doi.org/10.1038/548396a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/548396a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing