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Cell cycle

Continuous chromatin changes

DNA is packaged in the cell as chromatin, which folds into organized domains. Mapping of chromatin contacts in single cells sheds light on the dynamic evolution of these domains between cell divisions. See Article p.61

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Figure 1: Changes in dynamic chromosome folding during interphase.


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  1. Naumova, N. et al. Science 342, 948–953 (2013).

    Article  ADS  CAS  Google Scholar 

  2. Grand, R. S. et al. Nucleic Acids Res. 42, 12585–12599 (2014).

    Article  CAS  Google Scholar 

  3. Dileep, V. et al. Genome Res. 25, 1104–1113 (2015).

    Article  CAS  Google Scholar 

  4. Nagano, T. et al. Nature 547, 61–67 (2017).

    Article  ADS  CAS  Google Scholar 

  5. Denker, A. & de Laat, W. Genes Dev. 30, 1357–1382 (2016).

    Article  CAS  Google Scholar 

  6. Rao, S. S. P. et al. Cell 159, 1665–1680 (2014).

    Article  CAS  Google Scholar 

  7. Dixon, J. R. et al. Nature 485, 376–380 (2012).

    Article  ADS  CAS  Google Scholar 

  8. Nora, E. P. et al. Cell 169, 930–944 (2017).

    Article  CAS  Google Scholar 

  9. Zuin, J. et al. Proc. Natl Acad. Sci. USA 111, 996–1001 (2014).

    Article  ADS  CAS  Google Scholar 

  10. Schwarzer, W. et al. Preprint at bioRxiv (2016).

  11. Kubo, N. et al. Preprint at bioRxiv (2017).

  12. Flyamer, I. M. et al. Nature 544, 110–114 (2017).

    Article  ADS  CAS  Google Scholar 

  13. Stevens, T. J. et al. Nature 544, 59–64 (2017).

    Article  ADS  CAS  Google Scholar 

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Correspondence to Robert A. Beagrie or Ana Pombo.

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Biological techniques: Chromosomes captured one by one

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Beagrie, R., Pombo, A. Continuous chromatin changes. Nature 547, 34–35 (2017).

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