Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Immunology, one cell at a time

Analysing the DNA, RNA and protein of single cells is transforming our understanding of the immune system, say Amir Giladi and Ido Amit.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout


  1. Zeisel, A. et al. Science 347, 1138–1142 (2015).

    Article  ADS  CAS  Google Scholar 

  2. Grün, D. et al. Nature 525, 251–255 (2015).

    Article  ADS  Google Scholar 

  3. Lavin, Y. et al. Cell 159, 1312–1326 (2014).

    Article  CAS  Google Scholar 

  4. Kumar, V., Patel, S., Tcyganov, E. & Gabrilovich, D. I. Trends Immunol. 37, 208–220 (2016).

    Article  CAS  Google Scholar 

  5. Hume, D. A. Mucosal Immunol. 1, 432–441 (2008).

    Article  CAS  Google Scholar 

  6. Tanay, A. & Regev, A. Nature 541, 331–338 (2017).

    Article  ADS  CAS  Google Scholar 

  7. Jaitin, D. A. et al. Cell 167, 1883–1896 (2016).

    Article  CAS  Google Scholar 

  8. Junker, J. P. & van Oudenaarden, A. Cell 157, 8–11 (2014).

    Article  CAS  Google Scholar 

  9. McKenna, A. et al. Science 353, aaf7907 (2016).

    Article  Google Scholar 

  10. Jaitin, D. A. et al. Science 343, 776–779 (2014).

    Article  ADS  CAS  Google Scholar 

  11. Gury-BenAri, M. et al. Cell 166, 1231–1246 (2016).

    Article  CAS  Google Scholar 

  12. Paul, F. et al. Cell 163, 1663–1677 (2015).

    Article  CAS  Google Scholar 

  13. Tirosh, I. et al. Science 352, 189–196 (2016).

    Article  ADS  CAS  Google Scholar 

  14. Lavin, Y. et al. Cell 169, 750–765 (2017).

    Article  CAS  Google Scholar 

  15. Keren-Shaul, H. et al. Cell 169, 1276–1290 (2017).

    Article  CAS  Google Scholar 

  16. Becattini, S. et al. Science 347, 400–406 (2015).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding authors

Correspondence to Amir Giladi or Ido Amit.

Additional information

Tweet Follow @NatureNews

Related links

Related links

Related links in Nature Research

Single-cell genome sequencing: current state of the science 2016-Jan-25

Genomics: The single life 2012-Oct-31

Single-cell analysis: The deepest differences 2011-Nov-30

Single-cell genomics 2008-Mar-01

Single-cell genomics 2006-Jun-01

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Giladi, A., Amit, I. Immunology, one cell at a time. Nature 547, 27–29 (2017).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing