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Metastasis

Lymphatic detours for cancer

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The growth factor MIDKINE, which is secreted by skin tumours called melanomas, stimulates the formation of lymphatic vessels at distant lymph nodes and organ sites, paving the way for metastatic cancer spread. See Letter p.676

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Figure 1: A previously undiscovered route to metastasis.

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Correspondence to Ayuko Hoshino or David Lyden.

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Hoshino, A., Lyden, D. Lymphatic detours for cancer. Nature 546, 609–610 (2017). https://doi.org/10.1038/546609a

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