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Molecular biology

RNA editing packs a one-two punch

Optimal protein synthesis requires bases in transfer RNAs to be modified. A key modification has been shown to involve an unusual two-step mechanism that entails the sequential activities of two enzymes. See Letter p.494

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Figure 1: Two-step mechanism for RNA editing.

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Correspondence to William T. Yewdell or Jayanta Chaudhuri.

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Yewdell, W., Chaudhuri, J. RNA editing packs a one-two punch. Nature 542, 420–421 (2017). https://doi.org/10.1038/542420a

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