The News & Views article 'Cancer genomics: spot the difference' by Noah D. Peyser and Jennifer R. Grandis (Nature 541, 162–163; 2017) incorrectly stated that drugs that inhibit the activity of the protein KEAP1, which itself inhibits the transcription factor NRF2, could be used to combat activating mutations in the gene that encodes NRF2. Instead, it should have stated that this pathway could potentially be targeted for therapeutic use in certain oesophageal cancers if drugs are developed to inhibit mutant, activated NRF2.