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Supramolecular chemistry

Unexplored territory for self-assembly

Cage-like structures can self-assemble from suitable metal ions and organic linkers, but the size of the assemblies was limited. The surprise discovery of a new series of cages opens up fresh horizons for self-assembly. See Letter p.563

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Figure 1: Self-assembling molecular polyhedra.


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  1. Fujita, D. et al. Nature 540, 563–566 (2016).

    CAS  ADS  Article  Google Scholar 

  2. Smulders, M. M. J., Riddell, I. A., Browne, C. & Nitschke, J. R. Chem. Soc. Rev. 42, 1728–1754 (2013).

    CAS  Article  Google Scholar 

  3. Nicolaou, K. C. et al. Nature 392, 264–269 (1998).

    CAS  ADS  Article  Google Scholar 

  4. Kramer, R., Lehn, J. M. & Marquis-Rigault A. Proc. Natl Acad. Sci. USA 90, 5394–5398 (1993).

    CAS  ADS  Article  Google Scholar 

  5. Harris, K., Fujita, D. & Fujita, M. Chem. Commun. 49, 6703–6712 (2013).

    CAS  Article  Google Scholar 

  6. Suzuki, K., Tominaga, M., Kawano, M. & Fujita, M. Chem. Commun. 1638–1640 (2009).

  7. Tominaga, M. et al. Angew. Chem. Int. Edn 43, 5621–5625 (2004).

    CAS  Article  Google Scholar 

  8. Sun, Q.-F. et al. Science 328, 1144–1147 (2010).

    CAS  ADS  Article  Google Scholar 

  9. Fujita, D. et al. Chem 1, 91–101 (2016).

    CAS  Article  Google Scholar 

  10. Brinkmann, G. & Deza, M. J. Chem. Inf. Comput. Sci. 40, 530–541 (2000).

    CAS  Article  Google Scholar 

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Correspondence to Florian Beuerle.

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Beuerle, F. Unexplored territory for self-assembly. Nature 540, 529–530 (2016).

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