Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell biology

The organelle replication connection

Subjects

Live-cell imaging reveals that a functional interaction occurs between two different organelles: contact between the endoplasmic reticulum and mitochondria is needed for mitochondrial DNA replication and division.

This is a preview of subscription content, access via your institution

Access options

Figure 1: The cellular location of mitochondrial DNA replication.

Notes

  1. See all news & views

References

  1. Pernas, L. & Scorrano, L. Annu. Rev. Physiol. 78, 505–531 (2015).

    Article  Google Scholar 

  2. Lewis, S. C., Uchiyama, L. F. & Nunnari, J. Science 353, aaf5549 (2016).

    Article  Google Scholar 

  3. Jaalouk, D. E. & Lammerding, J. Nature Rev. Mol. Cell Biol. 10, 63–73 (2009).

    Article  CAS  Google Scholar 

  4. Friedman, J. R. et al. Science 334, 358–362 (2011).

    Article  ADS  CAS  Google Scholar 

  5. Murley, A. et al. eLife 2, e00422 (2013).

    Article  ADS  Google Scholar 

  6. Kornmann, B. et al. Science 325, 477–481 (2009).

    Article  ADS  CAS  Google Scholar 

  7. de Brito, O. M. & Scorrano, L. Nature 456, 605–610 (2008).

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Elena Ziviani or Luca Scorrano.

Related links

Related links

Related links in Nature Research

Cell biology: Choreography of protein synthesis

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ziviani, E., Scorrano, L. The organelle replication connection. Nature 538, 326–327 (2016). https://doi.org/10.1038/538326b

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/538326b

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing