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Physiology

Stressed-out chromatin promotes longevity

Two studies reveal that early-life malfunction in organelles called mitochondria brings about lasting changes in how DNA is packaged. These alterations have consequences for cellular stress responses and organismal longevity.

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Figure 1: Coordinated responses to mitochondrial stress.

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Correspondence to Siu Sylvia Lee or Jessica K. Tyler.

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Lee, S., Tyler, J. Stressed-out chromatin promotes longevity. Nature 534, 625–626 (2016). https://doi.org/10.1038/534625a

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