If organic molecules were trees, then the numerous carbon–hydrogen bonds within them would be leaves. A catalyst that targets one 'leaf' out of many similar other ones looks set to be a huge leap for synthetic chemistry. See Letter p.230
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Liao, K., Negretti, S., Musaev, D. G., Bacsa, J. & Davies, H. M. L. Nature 533, 230–234 (2016).
Labinger, J. A. & Bercaw, J. E. Nature 417, 507–514 (2002).
Arndtsen, B. A., Bergman, R. G., Mobley, T. A. & Peterson T. H. Acc. Chem. Res. 28, 154–162 (1995).
Brückl, T., Baxter, R. D., Ishihara, Y. & Baran, P. S. Acc. Chem. Res. 45, 826–839 (2012).
Neufeldt, S. R. & Sanford, M. S. Acc. Chem. Res. 45, 936–946 (2012).
Davies, H. M. L. & Beckwith, R. E. J. Chem. Rev. 103, 2861–2903 (2003).
Davies, H. M. L. & Morton, D. Chem. Soc. Rev. 40, 1857–1869 (2011).
Related links in Nature Research
Rights and permissions
About this article
Cite this article
Yang, K., Engle, K. Precision pruning of molecules. Nature 533, 183–184 (2016). https://doi.org/10.1038/533183a