In mice, a high-fat diet has now been found to induce intestinal progenitor cells to adopt a more stem-cell-like fate, altering the size of the gut and increasing tumour incidence. See Article p.53
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Luo, C., Puigserver, P. Dietary fat promotes intestinal dysregulation. Nature 531, 42–43 (2016). https://doi.org/10.1038/531042a