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In retrospect

A century of phage lessons

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One hundred years after the first description of viruses that infect bacterial cells, the contribution of these bacteriophages to fundamental biology, biotechnology and human health continues unabated and deserves celebration.

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Figure 1: Bacteriophage in action.

a, Ref. 15; b, Graham Beards/CC-BY-3.0; c, Ref. 16

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References

  1. Twort, F. W. Lancet 186, 1241–1243 (1915).

    Article  Google Scholar 

  2. Hershey, A. D. & Chase, M. J. Gen. Physiol. 36, 39–56 (1952).

    Article  CAS  PubMed  Google Scholar 

  3. Sanger, F. et al. J. Mol. Biol. 125, 225–246 (1978).

    Article  CAS  PubMed  Google Scholar 

  4. Hendrix, R. W., Lawrence, J. G., Hatfull, G. F. & Casjens, S. Trends Microbiol. 8, 504–508 (2000).

    Article  CAS  PubMed  Google Scholar 

  5. Breitbart, M. et al. Proc. Natl Acad. Sci. USA 99, 14250–14255 (2002).

    Article  ADS  CAS  PubMed  Google Scholar 

  6. Nash, H. A. Annu. Rev. Genet. 15, 143–167 (1981).

    Article  CAS  PubMed  Google Scholar 

  7. Georgopoulos, C. Genetics 174, 1699–1707 (2006).

    Article  CAS  PubMed  Google Scholar 

  8. Luria, S. E. & Delbrück, M. Genetics 28, 491–511 (1943).

    CAS  PubMed Central  PubMed  Google Scholar 

  9. Vogelstein, B. et al. Science 339, 1546–1558 (2013).

    Article  ADS  CAS  PubMed  Google Scholar 

  10. Craigie, R. & Bushman, F. D. Cold Spring Harb. Perspect. Med. 2, a006890 (2012).

    Article  PubMed  Google Scholar 

  11. Wommack, K. E. & Colwell, R. R. Microbiol. Mol. Biol. Rev. 64, 69–114 (2000).

    Article  CAS  PubMed  Google Scholar 

  12. Reyes, A. et al. Nature 466, 334–338 (2010).

    Article  ADS  CAS  PubMed  Google Scholar 

  13. Barr, J. J. et al. Proc. Natl Acad. Sci. USA 110, 10771–10776 (2013).

    Article  ADS  CAS  PubMed  Google Scholar 

  14. Sharon, I. N. et al. ISME J. 5, 1178–1190 (2011).

    Article  CAS  PubMed  Google Scholar 

  15. Ruska, H. Naturwissenschaften 28, 45–46 (1940).

    Article  ADS  CAS  Google Scholar 

  16. Hu, B., Margolin, W., Molineux, I. J. & Liu, J. Proc. Natl Acad. Sci. USA 112, E4919–E4928 (2015).

    Article  ADS  CAS  PubMed  Google Scholar 

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Correspondence to Forest Rohwer or Anca M. Segall.

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Rohwer, F., Segall, A. A century of phage lessons. Nature 528, 46–47 (2015). https://doi.org/10.1038/528046a

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