The epithelial cells that line the intestine have been found to sense tight attachment of bacteria, and to respond by producing proteins that shape the effector functions of the immune system's TH17 cells.
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Bel, S., Hooper, L. A bacterial nudge to T-cell function. Nature 526, 328–330 (2015). https://doi.org/10.1038/526328a
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DOI: https://doi.org/10.1038/526328a