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Longevity

Mapping the path to a longer life

Inhibiting the PI3K branch of the cell signalling induced by insulin and insulin-like growth factor can extend lifespan. The finding that inhibiting the RAS branch also extends lifespan in flies suggests a new target for anti-ageing drugs.

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Figure 1: IIS and lifespan.

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Correspondence to Morris F. White.

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White, M. Mapping the path to a longer life. Nature 524, 170–171 (2015). https://doi.org/10.1038/524170a

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