Table 3 TDT results for the SNPs showing association in SYPL, LAMB1, and NRCAM

From: Mutation screening and association analysis of six candidate genes for autism on chromosome 7q

     Paternal Maternal Combined
SNP ID ASP group Allele % TR NT χ 2 TR NT χ 2 TR NT χ 2
SYPLint2 219 ASP Allele A 23.9 65 51 1.69 61 39 4.84 140 104 5.31
   Allele G 76.1 51 65 1.69 39 61 4.84 104 140 5.31
     P=0.1936 P=0.0278 P=0.0212
  145 male ASP Allele A 23.4 47 39 0.74 32 25 0.86 87 72 1.42
   Allele G 76.6 39 47 0.74 25 32 0.86 72 87 1.42
     P=0.3897 P=0.3537 P=0.2334
LAMB1 × 30 219 ASP Allele C 2.5 15 4 6.37 10 6 1.00 25 10 6.43
   Allele T 97.5 4 15 6.37 6 10 1.00 10 25 6.43
     P=0.0116 P=0.3173 P=0.0112
  145 male ASP Allele C 2.0 13 0 13.0 2 2 0.00 15 2 9.94
   Allele T 98.0 0 13 13.0 2 2 0.00 2 15 9.94
     P=0.0003 P=1.0000 P=0.0016
NRCAM rs1269622 219 ASP Allele A 56.1 56 35 4.85 49 32 3.57 138 100 6.07
   Allele G 43.9 35 56 4.85 32 49 3.57 100 138 6.07
     P=0.0276 P=0.0588 P=0.0135
  145 male ASP Allele A 57.1 36 25 1.98 36 22 3.38 93 68 3.88
   Allele G 42.9 25 36 1.98 22 36 3.38 68 93 3.88
     P=0.1593 P=0.0660 P=0.0489
NRCAM rs722519 219 ASP Allele A 14.7 15 35 8.00 22 31 1.53 45 74 7.07
   Allele G 85.3 35 15 8.00 31 22 1.53 74 45 7.07
     P=0.0047 P=0.2161 P=0.0078
  145 male ASP Allele A 13.7 8 17 3.24 15 21 1.00 29 44 3.08
   Allele G 86.3 17 8 3.24 21 15 1.00 44 29 3.08
     P=0.0718 P=0.3173 P=0.0793
NRCAM rs3763463 219 ASP Allele C 9.2 4 17 8.05 21 25 0.35 31 48 3.66
   Allele G 90.8 17 4 8.05 25 21 0.35 48 31 3.66
     P=0.0045 P=0.4583 P=0.0668
  145 male ASP Allele C 9.7 3 11 4.57 14 19 0.76 22 35 2.96
   Allele G 90.3 11 3 4.57 19 14 0.76 35 22 2.96
     P=0.0325 P=0.3833 P=0.0853