Table 2 Modeling the decay of disequilibrium with distance, estimated for autosomes, X-chromosome and four different genomic regions

From: Linkage disequilibrium in young genetically isolated Dutch population

  No. Model parameters (H1) Variance explained H 1 vs H 2 H 0 vs H 1
Region D′ cp H T (%) P A P B P A P B
Autosomes 11302 0.057 (0.05–0.067) 12 (10.5–13.9) 4.36 0.76 0.63 <0.0001 c <1/2500
Autosomesa 104 0.069 (0.044–0.101) 15.8 (4.4–28.6) 5.72 0.9 0.56 0.014 0.004
X-chromosomesb 922 0.053 (0.028–0.090) 12.8 (5.1–28.1) 2.58 0.063 0.026 b <0.0001 0.001
3p12 28 0.299 (0.160– 0.462) 200.8 (80.7–335) 39.3 0.73 0.38 0.0003 <1/2500
3p13 120 0.145 (0.043– 0.350) 63.8 (3.7–171.2) 8.16 0.23 0.11 0.002 0.015
10q26 66 0.241 (0.009– 1) 1015 (19–2292.3) 15.7 0.42 0.17 0.001 0.025
18p11 105 0.124 (0.032– 0.179) 289.5 (14.8–571.3) 7.07 0.12 0.1 0.006 0.001
  1. The number of Dcp values used is given in brackets. Parameter estimates (95% bootstrap confidence interval) and percent of variance explained for the accepted hypotheses and P-value coming from F-ratio test (PA) and bootstrap (PB) are shown. P-values less than 0.05 are in bold.
  2. aOnly adjacent marker pairs separated by at least 20 cM used.
  3. bParameters of H2 model are (H=0.06 (0.038–0.126), L=0.006 (0.000–0.011), T=19.4 (11.6–367.7)).