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Molecular biology

RNA modification does a regulatory two-step

The m6A structural modification of RNA regulates gene expression. It has now been found to mediate an unusual control mechanism: by altering the structure of RNA, m6A allows a regulatory protein to bind to that RNA. See Letter p.560

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Figure 1: Regulation of alternative splicing by the m6A RNA modification.

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Correspondence to Dominik Theler or Frédéric H.-T. Allain.

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Theler, D., Allain, FT. RNA modification does a regulatory two-step. Nature 518, 492–493 (2015). https://doi.org/10.1038/518492a

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