The idea of two sexes is simplistic. Biologists now think there is a wider spectrum than that.
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References
James, P. A., Rose, K., Francis, D. & Norris, F. Am. J. Med. Genet. A 155, 2484–2488 (2011).
Arboleda, V. A., Sandberg, D. E. & Vilain, E. Nature Rev. Endocrinol. 10, 603–615 (2014).
Sinclair, A. H. et al. Nature 346, 240–244 (1990).
Berta, P. et al. Nature 348, 448–450 (1990).
Jordan, B. K. et al. Am. J. Hum. Genet. 68, 1102–1109 (2001).
Tomaselli, S. et al. PLoS ONE 6, e16366 (2011).
Uhlenhaut, N. H. et al. Cell 139, 1130–1142 (2009).
Matson, C. K. et al. Nature 476, 101–104 (2011).
Hughes, I. A., Houk, C., Ahmed, S. F., Lee, P. A. & LWPES1/ESPE2 Consensus Group Arch. Dis. Child. 91, 554–563 (2006).
El-Khairi, R. & Achermann, J. C. Semin. Reprod. Med. 30, 374–381 (2012).
Sherwani, A. Y. et al. Int. J. Surg. Case Rep. 5, 1285–1287 (2014).
Tachon, G. et al. Hum. Reprod. 29, 2814–2820 (2014).
Bianchi, D. W., Zickwolf, G. K., Weil, G. J., Sylvester, S. & DeMaria, M. A. Proc. Natl Acad. Sci. USA 93, 705–708 (1996).
Maloney, S. et al. J. Clin. Invest. 104, 41–47 (1999).
Chan, W. F. N. et al. PLoS ONE 7, e45592 (2012).
Zeng, X. X. et al. Stem Cells Dev. 19, 1819–1830 (2010.
Link, J. C., Chen, X., Arnold, A. P. & Reue, K. Adipocyte 2, 74–79 (2013).
Penaloza, C. et al. FASEB J. 23, 1869–1879 (2009).
Warne, G. L. Sex Dev. 2, 268–277 (2008).
Baxter, R. M. et al. J. Clin. Endocrinol. Metab. 100, E333–E344 (2014).
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Ainsworth, C. Sex redefined. Nature 518, 288–291 (2015). https://doi.org/10.1038/518288a
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DOI: https://doi.org/10.1038/518288a
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