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Chemical biology

How to minimalize antibodies

The success of antibodies as pharmaceuticals has triggered interest in crafting much smaller mimics. A crucial step forward has been taken with the chemical synthesis of small molecules that recruit immune cells to attack cancer cells.

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Figure 1: Bridging target and effector cells.

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Correspondence to Christoph Rader.

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Rader, C. How to minimalize antibodies. Nature 518, 38–39 (2015). https://doi.org/10.1038/518038a

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