The repurposing of a bacterial defence system known as CRISPR into a potent activator of gene expression in human cells enables powerful studies of gene function, as exemplified in cancer cells. See Article p.583
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Cho, S., Chang, H. CRISPR engineering turns on genes. Nature 517, 560–562 (2015). https://doi.org/10.1038/517560a
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DOI: https://doi.org/10.1038/517560a
