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Depression

The best way forward

Conventional behavioural mouse models of depression are often used to study the disorder, but cannot capture the full picture of the human disease. Here, scientists present two views about the best research strategies to adopt if treatments are to be improved.

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Figure 1: Approaches to drug discovery for depression.

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Correspondence to Lisa M. Monteggia or Robert C. Malenka.

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Monteggia, L., Malenka, R. & Deisseroth, K. The best way forward. Nature 515, 200–201 (2014). https://doi.org/10.1038/515200a

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