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Structural biology

Enzyme–chromatin complex visualized

The structure of an enzyme that is bound to a nucleosome — a protein complex around which DNA is wrapped — reveals how contacts between the two orient the enzyme so that it can modify a specific amino-acid residue. See Article p.591

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Figure 1: Enzyme–nucleosome contacts dictate substrate specificity.

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Correspondence to Jürg Müller or Christoph W. Müller.

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Müller, J., Müller, C. Enzyme–chromatin complex visualized. Nature 514, 572–573 (2014). https://doi.org/10.1038/514572a

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