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Cell biology

Short RNAs and shortness of breath

The simultaneous deletion of six RNA molecules in mice has been found to cause respiratory and fertility defects, owing to improper assembly of structures called cilia on the cell surface. See Article p.115

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Figure 1: Ciliogenesis.


  1. Tsang, W. Y. & Dynlacht, B. D. Cilia 2, 9 (2013).

    CAS  Article  Google Scholar 

  2. Song, R. et al. Nature 510, 115–120 (2014).

    ADS  CAS  Article  Google Scholar 

  3. Lizé, M., Herr, C., Klimke, A., Bals, R. & Dobbelstein, M. Cell Cycle 9, 4579–4583 (2010).

    Article  Google Scholar 

  4. Martinez-Anton, A. et al. Am. J. Respir. Cell Mol. Biol. 49, 384–395 (2013).

    CAS  Article  Google Scholar 

  5. Marcet, B. et al. Nature Cell Biol. 13, 693–699 (2011).

    CAS  Article  Google Scholar 

  6. Spektor, A., Tsang, W. Y., Khoo, D. & Dynlacht, B. D. Cell 130, 678–690 (2007).

    CAS  Article  Google Scholar 

  7. Flynt, A. S. & Lai, E. C. Nature Rev. Genet. 9, 831–842 (2008).

    CAS  Article  Google Scholar 

  8. Cao, J. et al. Nature Cell Biol. 14, 697–706 (2012).

    CAS  Article  Google Scholar 

  9. Chen, Z., Indjeian, V. B., McManus, M., Wang, L. & Dynlacht, B. D. Dev. Cell 3, 339–350 (2002).

    CAS  Article  Google Scholar 

  10. Li, J. et al. Nature 495, 255–259 (2013).

    ADS  CAS  Article  Google Scholar 

  11. D'Angiolella, V. et al. Nature 466, 138–142 (2010).

    ADS  CAS  Article  Google Scholar 

  12. Lai, Y. et al. J. Allergy Clin. Immunol. 128, 1207–1215.e1 (2011).

    CAS  Article  Google Scholar 

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Correspondence to Irma Sánchez or Brian D. Dynlacht.

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Sánchez, I., Dynlacht, B. Short RNAs and shortness of breath. Nature 510, 40–42 (2014).

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