Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell biology

Short RNAs and shortness of breath

The simultaneous deletion of six RNA molecules in mice has been found to cause respiratory and fertility defects, owing to improper assembly of structures called cilia on the cell surface. See Article p.115

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Ciliogenesis.

References

  1. Tsang, W. Y. & Dynlacht, B. D. Cilia 2, 9 (2013).

    Article  CAS  Google Scholar 

  2. Song, R. et al. Nature 510, 115–120 (2014).

    Article  ADS  CAS  Google Scholar 

  3. Lizé, M., Herr, C., Klimke, A., Bals, R. & Dobbelstein, M. Cell Cycle 9, 4579–4583 (2010).

    Article  Google Scholar 

  4. Martinez-Anton, A. et al. Am. J. Respir. Cell Mol. Biol. 49, 384–395 (2013).

    Article  CAS  Google Scholar 

  5. Marcet, B. et al. Nature Cell Biol. 13, 693–699 (2011).

    Article  CAS  Google Scholar 

  6. Spektor, A., Tsang, W. Y., Khoo, D. & Dynlacht, B. D. Cell 130, 678–690 (2007).

    Article  CAS  Google Scholar 

  7. Flynt, A. S. & Lai, E. C. Nature Rev. Genet. 9, 831–842 (2008).

    Article  CAS  Google Scholar 

  8. Cao, J. et al. Nature Cell Biol. 14, 697–706 (2012).

    Article  CAS  Google Scholar 

  9. Chen, Z., Indjeian, V. B., McManus, M., Wang, L. & Dynlacht, B. D. Dev. Cell 3, 339–350 (2002).

    Article  CAS  Google Scholar 

  10. Li, J. et al. Nature 495, 255–259 (2013).

    Article  ADS  CAS  Google Scholar 

  11. D'Angiolella, V. et al. Nature 466, 138–142 (2010).

    Article  ADS  CAS  Google Scholar 

  12. Lai, Y. et al. J. Allergy Clin. Immunol. 128, 1207–1215.e1 (2011).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Irma Sánchez or Brian D. Dynlacht.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sánchez, I., Dynlacht, B. Short RNAs and shortness of breath. Nature 510, 40–42 (2014). https://doi.org/10.1038/510040a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/510040a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing